Scan the title graphic. Some of the characters look different than the others, don't they?

You're not anagramming. You're not extracting the letters that are different.

The characters that are different are not more or less important than the others - just different. They are all important and required to get the answer.

Fun fact: “sans” means “without”.

You have two types of letters: serif and sans-serif. With and without. Yes and no.

There are exactly 20 characters (not including spaces) in the graphic.

The answer is 4 letters.

You can split the 20 characters into 4 groups of 5.

Convert the characters to binary (serif=1 and sans-serif=0). Split them into 5-bit binary. Conver to numbers and then get the corresponding letter of the alphabet.